This is a widespread mitosporic (lacking a sexual state) fungus of the classification group "Hyphomycetes". There is little information regarding toxicity or allergenicity, but it is known to rarely be the causative agent for human keratitis (infection of the cornea).

Various species of this genus may be identified from indoor sampling (one species in particular, Trichocladium uniseptatum, is found regularly on indoor environmental surfaces, especially wood). Outdoors, it is found on dead wood, stems or twigs, tubers of various plants, pine needles, other plant debris, and in soils. It is notable that this microbe has been associated with black root rot, as an aggressive plant pathogen.

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